Citation Information :
Goyal A, Jain G, Jain A, Ansari T, Bumb SS. A New Era of Local Anaesthetic Agent: Centbucridine. Arch Craniofac Sci 2013; 1 (3):40-43.
One century after the clinical introduction of cocaine, local anesthesia remains the most important method of pain control in dentistry. Many local anesthetics have been marketed since 1884, and it is likely that attempts to produce drugs that enhance anesthetic efficacy, reduce systemic and local toxicity, and increase nociceptive selectivity, will continue. Centbucridine is a non-ester, non-amide group LA and has not been comprehensively studied in the dental setting and the objective was to compare it to Lignocaine. This was a randomized study comparing the onset time, duration, depth and cardiovascular parameters between Centbucridine (0.5%) and Lignocaine (2%). The study was conducted in the department of oral and maxillofacial surgery of our dental college in on patients attending for the extraction of lower molars.
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