Citation Information :
Vakade CD, Rai KK, Kumar HS, Batra J. Efficacy of Post-Operative Antibiotics in the Management of Facial Fractures: Single Day Against Five Day Regimen. Arch Craniofac Sci 2013; 1 (6):76-80.
Based on the duration of antibiotics received post-operatively, 56 patients with maxillofacial fractures were divided into two groups, Group A patients received antibiotics for not more than 24 hr. in the post-operative period whereas Group B patients received antibiotics for duration of five days post-operatively. They were then followed up at 7th, 14th, 28th, and 42nd day for signs of infection such as pus discharge, fever etc by using a standardized form. Patients having any signs of infection were counted as infected.
In the Group A, 8 out of 25 subjects (32%) developed infection. In Group B, 10 out of 31 subjects (32.2%) developed infection. Statistical analysis using chi-square test distribution showed that this difference in proportions was not significant.
This study showed that the use of postoperative prophylactic antibiotics does not have a statistically significant effect on postoperative infection rates in the surgical management of facial fractures.
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